Liver transplantation has become a victim of its own success. An increasing number of patients are referred for liver transplantation, but the number of available grafts has remained stagnant at best. The organ shortage is the only limiting factor to further application of liver transplantation.
Long-term islet allograft survival was achieved by a novel immunosuppressant regimen that included efalizumab, prompting Dr. Ron Shapiro to comment on the agent’s withdrawal from the market.
C4d is a reliable marker of antibody-mediated rejection in transplanted kidneys, but is it useful in pancreas transplantation? Dr. Ron Shapiro reports on a study that examines this issue.
I would like information on appropriate isolation policies for renal transplant patients who present with fever, pulmonary infection (of unknown origin), septicemia, and/or rejection. Do such conditions indicate isolation precautions?
Early bone loss after kidney transplantation is a common problem that can lead to bone fracture. Does prophylactic use of teriparatide improve bone mineral density after kidney transplantation?
A 32-year-old male with Down's syndrome recently underwent a pancreas and renal transplantation and is doing well 8 weeks after surgery. In general, what are your thoughts about transplanting people with Down's syndrome?
Read response by Robert Stratta, MD, to question: How often is late hyperglycemia after pancreas transplantation ascribed to tacrolimus use; does it resolve with switch to cyclosporine or sirolimus?