- 1). Beta-lactam antibiotics include penicillins and cephalosporins. According to the University of Maryland Medical Center, this type of antibiotic is most effective in UTIs caused by Gram-positive organisms. Amoxicillin is now considered ineffective against E. coli bacteria in up to 25 percent of cases.
- 2). Trimethoprim-sulfamethoxazole (TMP-SMX) is a typical treatment in, usually, a three-day course.
- 3). According to the University of Maryland Medical Center, antibiotic-resistant strains of E. coli are the most common cause of UTIs. Quinolones (or fluoroquinolone) are now the most commonly prescribed antibiotic for UTIs. Trimethoprim-sulfamethoxazole formerly held that title.
- 4). Your doctor may decide one of the above classes of antibiotics will not be effective. Other types include tetracyclines, aminoglycosides, nitrofurantoin and fosfomycin.
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