- Naproxen constricts blood vessels, which then reduces kidney blood flow causing fluid retention resulting in a blood pressure rise. Together the constricted blood vessels plus decreased kidney perfusion (lower blood flow) raise the blood pressure. Mild to severe blood pressure increases may occur.
- Naproxen takes direct aim at a catalyst, known as COX (cyclooxegenase) and blocks out COX to reduce the pain. By blocking the catalyst COX, inflammatory mediators like prostaglandins can not be released to heighten pain signals.
- Naproxen (Anaprox, Aleve) is classified as a Non-Steroidal Anti-inflammatory (NSAID) drug. Similar drugs in this category are Motrin and Advil, also known generically as ibuprofen, and available over the counter (OTC). Prescription strength doses are available for Naproxen and ibuprofen.
- Naproxen use includes, but is not limited to, arthritis, headache, ligament sprain, muscle strain, menstrual cramp, fever and gout, tendinitis and bursitis. Generally, any condition due to inflammation can be treated with Naproxen.
- Consult a physician if you take medications, are pregnant, or have any pre-existing medical conditions, especially heart, blood pressure, blood clotting, gastrointestinal (peptic ulcer), asthma, liver or kidney issues. Dose of drug and long-term use raise risks; however, short-term, low dose use in the appropriate setting for higher risk patients as described may be safe with physician guidance.
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