Advantages of MOT for Recipients
If organs were not scarce, there would be obvious advantages to MOT since the patient undergoes a single transplant surgery procedure versus having one transplant and then waiting an uncertain period for a transplant from a different donor. Such serial surgeries risk immunological sensitization after the first procedure and could plausibly require repeated induction therapy. The candidate's health might decline substantially prior to the second, delayed transplant. Additionally, some data suggest that, for SLK, receiving two organs from the same donor lowers the probability of kidney rejection. Also, for all transplant candidates wait-listed for a kidney as an additional organ, the need for dialysis in the peri-operative period or the adverse outcome of chronic dialysis if single-organ transplant takes place will increase the risk of death and hospitalization and worsen quality of life. However, in the setting of scarcity, we must consider the competing needs of all candidates, not only the needs of candidates who may derive benefit from MOT.