A novel agent, belatacept, may preserve renal function and improve long-term outcomes better than calcineurin inhibitors in kidney transplantation. Dr. Ron Shapiro discusses 2 pivotal trials.
We have a 51-year-old patient with alcoholic cirrhosis, postoperative day 21 after liver transplantation, with cyclosporine (CsA) neurotoxicity (seizures and stupor). CsA levels are therapeutic levels (300-400). How do you decrease the dose, what parameters do you use, and what is the best target ra
How common is polyomavirus (BKV) in renal allograft biopsies and what are the reliable differentiation points with respect to tubulo-interstitial rejection?
Dr. Ron Shapiro reports on whether the expression of intratubular vimentin and CD44 in 6-month protocol biopsies is a marker for development of interstitial fibrosis and tubular atrophy.
On September 15, the Food and Drug Administration changed the indications for valganciclovir (Valcyte) to include prevention of CMV disease in kidney, pancreas, and heart transplant patients.