Lack of Mobility
Even laptops aren't as mobile as most people would like and even then, they are very sensitive machines that require a lot of care. Being dependant on your computer means it dictates where you go. This can severely limit the activities you do in your day-to-day life. You can forget about things like swimming or high-impact activities like mountain biking. Even if you do take your computer along, there is a great possibility of breaking it outside your home.
Financial Strain
As a computer ages, you will need to upgrade it. Computers can be very expensive to replace and upgrade, but you can't rely on an out-of-date and failing machine. As new versions of programs come out and demand stronger computers, you will find yourself shelling out large sums of money for increasingly advanced computer parts. You can save some money by assembling the computer yourself, but if you try to keep on the cutting edge of computer technology, you had better have a large and steady income to support your tech habit.
Anxiety
While it may seem silly, people who have a dependence on computers can suffer anxiety when they do not have their technological companion. A computer serves as a good distraction from real-world problems. Without that distraction, the unhandled problems people face can come rushing back to bite them in the backside. A computer doesn't cure their problems, it just gives them something to tinker with and neglect the emotional turmoil they would otherwise have to face.
Ruining Relationships
It is hard for someone to try to talk to you when you have your nose pointed at a computer. Becoming overly dependent on computers can start to put a strain on your personal relationships. You can still communicate with your loved ones online, but it isn't the same as an intimate face-to-face meeting. A prolonged period of dependency on your computer can start forming a large rift between you and your family and friends.