This Searching is one of the methods used to patent search and analyze the protein and DNA sequences listed in patents and patent application provided by the client. It is very helpful in finding the similar patterns of molecules of two different proteins and DNA sequences and gives the exact sequence of matching molecules corresponding to each other. As we know that proteins are long chains of amino acids consisting of repeating patterns of A, C, G, T and U molecules. So, it is possible to find similar chains of these molecules between two distinct protein sequences with the help of specified algorithms and tools. This process is also called sequence searching.

The process of sequence searching starts with a query sequence provided by the client asking for other sequences having particular amount of similarities with Query. Then the patent analyst uses BLAST (Basic Local Alignment Search Tool) or any other similar tool like ENA to compare the query with other sequences in the database known as Subject Sequences. Here we have used BLAST tool to find the similar patterns among the Subjects and Queries.

Here you can find two boxes one under Query Sequence and another under Subject sequence. Now you just have to put the corresponding sequences there and choose the option BLAST. The result obtained contains the alignment details of the two sequences along with the number of matching molecules. This can be used to find the required information about our sequences regarding their lengths and molecule types.

Once we have obtained the required information about our sequences and their matching molecules the next step is to put it in a database and find the corresponding patents. This ends the process of sequence searching.

Sequence searching finds its importance in many biological as well as non-biological processes. In bioinformatics, a sequence alignment is a way of arranging the sequences of DNA, RNA, or protein to identify regions of similarity that may be a consequence of functional, structural, or evolutionary relationships between the sequences. A Sequence alignment are also used for non-biological sequences, such as those present in natural language or in financial data. this searching can also be helpful in forensics to compare different DNA sequences collected from various crime scenes. In the world of Life Sciences it finds its importance as a tool to analyze the functionality of various new formed sequences according to their matching ancestors.